Fat Will Eat Your Mind

It is already known that both excess visceral fat and the lifestyle choices needed to gain it - being sedentary and a high calorie diet - correlate with increased risk of many age-related conditions. Going beyond associations to matters of causation, it is worth noting that animal studies have shown that surgical removal of visceral fat increases life expectancy.
These recently published open access study results add to the existing stack of reasons to care about your weight and lifestyle choices:
The purpose of this study was to determine the association between visceral adipose tissue (VAT) and all-cause mortality. The sample included 1089 white men and women 18-84 years of age from the Pennington Center Longitudinal Study, a prospective cohort of participants assessed between 1995 and 2008, and followed for mortality until 31 December 2009. Abdominal VAT was measured [using] computed tomography. There were 27 deaths during an average of 9.1 years of follow-up. 

Source: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432185/

Niacin intake protect against the development or progression of Alzheimer’s disease

Nicotinamide restores cognition in AD transgenic mice via a mechanism involving sirtuin inhibition
and selective reduction of Thr231-phosphotau.

Source:http://www.ncbi.nlm....cles/PMC2617713


Cell Life Versus Cell Longevity: The Mysteries Surrounding the NAD+ Precursor Nicotinamide.
" In a similar vein, inhibition of PARP activity by nicotinamide may be critical for disorders such as Alzheimer’s disease.

More recently, sufficient dietary niacin intake examined in a series of patients aged 65 and older has been implicated as a potential factor to protect against the development or
progression of Alzheimer’s disease. "

Source:http://www.ncbi.nlm....cles/PMC2248696

Choline + Uridine: Build New Neurons and Protect Against Alzheimer’s

" Choline + Uridine: Build New Neurons and Protect Against Alzheimer’s "
Source:http://www.smart-pub...nst-Alzheimers/


Aging influences the
micro environment for adult and immature neurons in the brain, which may affect the proliferation and migration of neural stem/progenitor cells, and YKS has pharmacological potency for these  age-related events. These findings help to understand the physiology and pathology of the aged brain and provide an anti-aging strategy for the brain. "

Source:http://www.ncbi.nlm....t_uids=19729050


" YKS has improving activity for age-related increased anxiety and enhances serotonergic and dopaminergic transmissions in the aged PFC. These mechanisms provide information important for the treatment of anxiety in the elderly. "

Source:http://www.ncbi.nlm....t_uids=19799980